Set in Springfield, the average American town, the show focuses on the antics and everyday adventures of the Simpson family; Homer, Marge, Bart, Lisa and Maggie, as well as a virtual cast of thousands. Since the beginning, the series has been a pop culture icon, attracting hundreds of celebrities to guest star. The show has also made name for itself in its fearless satirical take on politics, media and American life in general.
Lisa tries to fit in with two college students by lying about her age. She finds that the college atmosphere is perfect for her, but her lie is soon discovered and she is shunned by her fellow elementary school students. Meanwhile, Bart is diagnosed with a weakened immune system after getting bitten by a Chinese mosquito and must live in a plastic, germ-free bubble.