Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
While House's staff tries to diagnose a woman whose uncontrollable muscle flailing caused her to crash her car, House and Stacy try to resolve their relationship issues once and for all. Cameron refuses to take her HIV test, wary of the results.