The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.
When Mulder and Scully try to discover what unseen force may have driven a scientist to commit suicide, they turn up a laboratory where extreme genetic experimentation has bred subjects possessing dangerous powers.