A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.
Grissom and his crew handle their highest profile case to date when the city's former chief of detectives is slain execution-style in his house following a wild party. Missing from the residence are the chief's trophy wife and their 7-year-old daughter. Catherine and Warrick follow the trail to Miami, and soon enlist the help of Horatio Caine.