Due to a political conspiracy, an innocent man is sent to death row and his only hope is his brother, who makes it his mission to deliberately get himself sent to the same prison in order to break the both of them out, from the inside out.
Bellick, now teamed up with Michael, Lincoln and Nika, sets out to find the money stolen by Westmoreland during the 1971 skyjacking. Kellerman targets Sara, who receives a long-awaited phone call. T-Bag gets a ride from an unsuspecting family. Abruzzi resumes the search for Fibonacci to settle the scores once and for all.