A group of laid-off workers bribed into working one last night discover that processing the last of their "inventory" will lead to cataclysmic consequences.
Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.
In 1959, an alien experiment crashes to earth and infects a fraternity member. They freeze the body, but in the modern day, two geeks pledging a fraternity accidentally thaw the corpse, which proceeds to infect the campus with parasites that transform their hosts into killer zombies.
Zed and Addison are beginning their final year at Seabrook High in the town that’s become a safe haven for monsters and humans alike. Zed is anticipating an athletic scholarship that will make him the first Zombie to attend college, while Addison is gearing up for Seabrook’s first international cheer-off competition. Then suddenly, extraterrestrial beings appear around Seabrook, provoking something other than friendly competition.
A couple's vacation to Ireland transforms into a nightmare as a virus spreads from slaughtered animals to humans, causing the dead to rise and feast on the living.
Conducting clandestine experiments within the morgue at Miskatonic University, scientist Herbert West reveals to a fellow graduate student his groundbreaking work concerning the re-animation of fresh corpses.