On a bitterly cold December night, a paranormal investigations team has set their sights on the bloody Hillcrest Sanatorium to answer the age old question: Is there life after death? With rumours of hauntings and local children gone missing, they may just get their answer the hard way when members of the team mysteriously disappear, leaving behind unnerving evidence.
A down-and-out Brooklyn detective is hired to track down a singer on an odyssey that will take him through the desperate streets of Harlem, the smoke-filled jazz clubs of New Orleans, and the swamps of Louisiana and its seedy underworld of voodoo.
After he's institutionalized in order to cover for his sister, a young man encounters a doctor who is turning his patients into flesh-eating psychopaths.