Famed monster slayer Gabriel Van Helsing is dispatched to Transylvania to assist the last of the Valerious bloodline in defeating Count Dracula. Anna Valerious reveals that Dracula has formed an unholy alliance with Dr. Frankenstein's monster and is hell-bent on exacting a centuries-old curse on her family.
The mysterious Count Orlok summons Thomas Hutter to his remote Transylvanian castle in the mountains. The eerie Orlok seeks to buy a house near Hutter and his wife, Ellen. After Orlok reveals his vampire nature, Hutter struggles to escape the castle, knowing that Ellen is in grave danger. Meanwhile Orlok's servant, Knock, prepares for his master to arrive at his new home.
British estate agent Renfield travels to Transylvania to meet with the mysterious Count Dracula, who is interested in leasing a castle in London and is, unbeknownst to Renfield, a vampire. After Dracula enslaves Renfield and drives him to insanity, the pair sail to London together, and as Dracula begins preying on London socialites, the two become the subject of study for a supernaturalist professor, Abraham Van Helsing.
Despite Jigsaw's death, and in order to save the lives of two of his colleagues, Lieutenant Rigg is forced to take part in a new game, which promises to test him to the limit.
An unnamed doctor has always had everything he's ever wanted, but that has only made him develop more extreme and depraved needs. He kidnaps a young couple in the prime of their life together and forces them into a game of torment that slowly extinguishes their hopes for survival.
As sadomasochistic yakuza enforcer Kakihara searches for his missing boss he comes across Ichi, a repressed and psychotic killer who may be able to inflict levels of pain that Kakihara has only dreamed of.
In a quiet suburban town in the summer of 1958, two recently orphaned sisters are placed in the care of their mentally unstable Aunt Ruth. But Ruth's depraved sense of discipline will soon lead to unspeakable acts of abuse and torture that involve her young sons, the neighborhood children, and one 12-year-old boy whose life will be changed forever.
A group of people awaken to find themselves prisoners in a mysterious house with no means of escape. They are each outfitted with electronic devices attached to the base of their skulls. The chemicals that the brain produces when in pain are collected by the devices, and when it collects a predetermined amount, the doors will be opened. In order to escape, they must hurt themselves and each other.
In an isolated family mansion, a group of rich 20-somethings decides to play Bodies Bodies Bodies, a game where one of them is secretly a "killer" while the rest tries to "escape". Things take a turn for the worse when real bodies start turning up, setting off a paranoid and dangerous chain of events.