Family man François Nouel is the number one fan of the Tour de France – an obsession that costs him his wife and his job. At a loose end, François meets a former sports manager, Rémi who encourages him to take the plunge and do the Tour himself. With nothing to lose, François sets off, always one day ahead of the race, attracting fellow amateurs, media coverage and cheering crowds. As obstacle after obstacle is thrown his way, and his family comes back on the scene, François discovers what is really most important in his life.
After standing in as best man for his longtime friend Carl Petersen, Randy Dupree loses his job, becomes a barfly and attaches himself to the newlywed couple almost permanently -- as their houseguest. But the longer Dupree camps out on their couch, the closer he gets to Carl's bride, Molly, leaving the frustrated groom wondering when his pal will be moving out.
Kyle and Mike are best friends who share a close bond — until Mike sleeps with Kyle’s fiancée. A stormy but enduring relationship ensues between Kyle, with limitless patience, and Mike, who only lives his life by sowing discord in that of others, across many years of laughter, heartbreak, and rage.