When virtually all of the residents of Piedmont, New Mexico, are found dead after the return to Earth of a space satellite, the head of the US Air Force's Project Scoop declares an emergency. A group of eminent scientists led by Dr. Jeremy Stone scramble to a secure laboratory and try to first isolate the life form while determining why two people from Piedmont - an old alcoholic and a six-month-old baby - survived. The scientists methodically study the alien life form unaware that it has already mutated and presents a far greater danger in the lab, which is equipped with a nuclear self-destruct device designed to prevent the escape of dangerous biological agents.
Robert Neville is a scientist who was unable to stop the spread of the terrible virus that was incurable and man-made. Immune, Neville is now the last human survivor in what is left of New York City and perhaps the world. For three years, Neville has faithfully sent out daily radio messages, desperate to find any other survivors who might be out there. But he is not alone.
As an epidemic of a lethal airborne virus - that kills within days - rapidly grows, the worldwide medical community races to find a cure and control the panic that spreads faster than the virus itself.
A deadly virus has spread across the globe. Contagion is everywhere, no one is safe, and no one can be trusted. Four friends race through the back roads of the American West on their way to a secluded utopian beach in the Gulf of Mexico where they could peacefully wait out the pandemic. Their plans take a grim turn when their car breaks down on an isolated road starting a chain of events that will seal their fates.
After a virus of epic proportions overwhelms the planet—with more infected than uninfected—humanity is losing its grip on survival and its only hope is finding a cure and keeping the infected contained. Lauren, a doctor, arrives in Los Angeles with her crack team to lead the hunt for uncontaminated civilian survivors, but nothing can prepare them for the blood-soaked mayhem they witness as they head into the Californian streets where everything is considered a trap.
Dr. Adrian Helmsley, part of a worldwide geophysical team investigating the effect on the earth of radiation from unprecedented solar storms, learns that the earth's core is heating up. He warns U.S. President Thomas Wilson that the crust of the earth is becoming unstable and that without proper preparations for saving a fraction of the world's population, the entire race is doomed. Meanwhile, writer Jackson Curtis stumbles on the same information. While the world's leaders race to build "arks" to escape the impending cataclysm, Curtis struggles to find a way to save his family. Meanwhile, volcanic eruptions and earthquakes of unprecedented strength wreak havoc around the world.
When an asteroid threatens to collide with Earth, NASA honcho Dan Truman determines the only way to stop it is to drill into its surface and detonate a nuclear bomb. This leads him to renowned driller Harry Stamper, who agrees to helm the dangerous space mission provided he can bring along his own hotshot crew. Among them is the cocksure A.J. who Harry thinks isn't good enough for his daughter, until the mission proves otherwise.
Ray Ferrier is a divorced dockworker and less-than-perfect father. Soon after his ex-wife and her new husband drop off his teenage son and young daughter for a rare weekend visit, a strange and powerful lightning storm touches down.
After an unprecedented series of natural disasters threatened the planet, the world's leaders came together to create an intricate network of satellites to control the global climate and keep everyone safe. But now, something has gone wrong: the system built to protect Earth is attacking it, and it becomes a race against the clock to uncover the real threat before a worldwide geostorm wipes out everything and everyone along with it.
Five young New Yorkers throw their friend a going-away party the night that a monster the size of a skyscraper descends upon the city. Told from the point of view of their video camera, the film is a document of their attempt to survive the most surreal, horrifying event of their lives.
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