The story revolves around a Basque Roman Catholic priest dedicated to committing as many sins as possible, a death metal salesman from Carabanchel, and the Italian host of a TV show on the occult. These go on a literal "trip" through Christmas-time Madrid to hunt for and prevent the reincarnation of the Antichrist.
While doing a series of reports on alternative energy sources, opportunistic reporter Kimberly Wells witnesses an accident at a nuclear power plant. Wells is determined to publicize the incident, but soon finds herself entangled in a sinister conspiracy to keep the full impact of the incident a secret.
A packed cruise ship traveling the Atlantic is hit and overturned by a massive wave, compelling the passengers to begin a dramatic fight for their lives.
A naive young man assumes a dead man's identity and finds himself embroiled in an underground world of power, violence, and chance where men gamble behind closed doors on the lives of other men.
Seth and Jonah are twins with a dangerous ability: telekinesis. Things start to spiral out of control as their classmates die in twisted and bizarre ways. Jealousy begins to divide them and soon they can no longer trust each other, leading up to a horrific battle against themselves.