After an overly ambitious businessman transports an 80-foot python to the United States, the beast escapes and starts to leave behind a trail of human victims. An FBI agent and a snake specialist come up with a plot to combat the creature by pitting it against a bioengineered, 70-foot boa constrictor. It's two great snakes that snake great together!
In the countryside, the boy Alan and his friend Becky steal a creepy wooden box with a powerful voodoo stick inside from his voodooistic neighbor. When the boy draws with the stick, his drunken father is attacked by a snake and vanishes. Years later, Alan and Becky are married to each other; while planting some flowers to celebrate the death of Alan's mother, Becky finds the box buried in the garden and she keeps the stick in her pocket. Meanwhile, five friends are traveling in a monster truck, drinking beer. The driver accidentally runs over Becky, but believes he had hit an animal. When Alan witnesses the hit-and-run and sees his wife dead, he uses the stick seeking revenge against the youngsters.
Dr. Emma Collins and her team are spending their third summer on the island of Little Happy studying the effect of climate change on the great white sharks who come to the nearby nursery every year to give birth. Along with the last two inhabitants of this former fishing village, their peaceful life is disrupted when a "scientific" team led by her ex-boyfriend and marine biologist Richard show up looking for three bull sharks who we soon learn aren't just any bull sharks.
Paleontologist Robert Trenton is called to Northeastern Antarctica near the Indian Ocean to help the FBI build an underground maximum-security military base and prison for the world's most dangerous criminals and terrorists, which is dubbed "New Alcatrax" by the staff. While building the prison, the staff accidentally awaken and unleash a prehistoric Boa Constrictor from its 200 year hibernation.
Mutant snakes survived a terrorist attack on a government laboratory, and they now threaten the town of Santa Mira Springs, California. Seismic activity has brought snakes to the surface, where residents are being bitten. Victims can transmit the virus to healthy persons. The military puts the town under quarantine. Local physicians try to control the epidemic, while the military is primarily concerned with keeping the virus a secret.
A set of vipers has been taken by scientists to mutate them to make a cure for cancer. As their experiment goes awry, the vipers escape into the woods - they're not only biting people, they're actually killing people, in a little town.
After an earthquake destroys their underwater station, six researchers must navigate two miles along the dangerous, unknown depths of the ocean floor to make it to safety in a race against time.
When a man is eaten alive by an unknown creature, the local Game Warden teams up with a paleontologist from New York to find the beast. Add to the mix an eccentric philanthropist with a penchant for "Crocs", and here we go! This quiet, remote lake is suddenly the focus of an intense search for a crocodile with a taste for live animals...and people!
Black Lake is now a crocodile sanctuary, surrounded by an electric fence. When the fence is left open, a high-school bus unknowingly enters the park. It's up to Reba and the Sheriff to save the kids from becoming crocodile food.
Detective Klaski investigates the death and mutilation of three men and soon crosses paths with Remy, an entomologist. Soon, he discovers that she is being stalked by a giant shape-shifting insect who is bent on taking over New York.
On the last working day of Sheriff Wayne, his small town is attacked by blood thirsty ravens that eat human flesh. Meanwhile his wife Cynthia visits a farm where a Mennonite family lives to say farewell to her friend Gretchen and discloses a dark secret about the origin of the fierce ravens.