The story, set in the backdrop of Nallore, a small town in Thoothukudi District, revolves around Sub-Inspector Durai Singam, a brave and just policeman who serves in his hometown primarily to fulfill his father’s wish. Durai Singam settles every dispute in his town patiently with his words of wisdom and resorts to force only when the situation demands it. Kavya, a city girl who comes on vacation to Nallore, falls in love with Durai Singam. Erimalai, Durai Singam's bumbling colleague and friend, often accompanies him.
Dangerous Men is a film with many characters, like Mina, whose life is shattered when two bikers with rape on their minds attack and kill Daniel, her fiancé. Driven by grief, she embarks on a killing rampage, wreaking vengeance upon all the men that she seductively lures into her trap. In her twisted world, cops and killers are all the same. David, Daniel's brother, is a cop who relentlessly pursues the killers, while facing a nest of drug dealers, followed by the FBI and the police SWAT team, also in hot pursuit. Mina, a victim of violence, carrying a twisted obsession for justice, is caught between opposing forces in a world of dangerous men.
A cop sets out to find a man who has been delivering too much of a good thing in this offbeat comedy. Police detective Martinez (Jesus Ochoa) has been handed a most unusual case -- a number of local prostitutes have been murdered, and it's up to Martinez to bring in the killer. What makes the case truly unusual, though, is the manner of death; it seems the hookers all died as a result of having orgasms so powerful they were literally fatal. Teaming up with cultural anthropologist Onofre (Daniel Giménez Cacho), Martinez hits the streets looking for clues, and eventually gets some unexpected help from Father Gorkisolo (Santiago Segura), a priest with a unusually deep knowledge of sexual matters. Asesino en Serio was the first feature film from director Antonio Urrutia; noted Mexican filmmaker Guillermo del Toro served as executive producer.
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