In 19th century Baltimore, Isabel Porter, a girl stricken with grief from her parents' untimely death, voluntarily checks herself into the Rosewood Institute. Subjected to bizarre and increasingly violent pseudo-scientific experiments in personality modification, brainwashing and mind control, she must escape the clutches of the Rosewood and exact her revenge, or else be forever lost.
An Oxford Medical School graduate takes a position at a mental institution and soon becomes obsessed with a female mental patient, but he has no idea of a recent and horrifying staffing change.
The crew of the colony ship Covenant, bound for a remote planet on the far side of the galaxy, discovers what they think is an uncharted paradise but is actually a dark, dangerous world.
Retired cop James Lasombra is asked by a friend to investigate the disappearance of her daughter, who seemingly packed in the night and left an ominous message on the bathroom mirror - "The Empty Man Made Me Do It." As he investigates this mysterious figure further, James begins to see and hear strange things, and is forced to come to terms with his past and what it means for his future.
Underwater deep-sea miners encounter a Soviet wreck and bring back a dangerous cargo to their base on the ocean floor with horrifying results. The crew of the mining base must fight to survive against a genetic mutation that hunts them down one by one.
After returning home from the Vietnam War, veteran Jacob Singer struggles to maintain his sanity. Plagued by hallucinations and flashbacks, Singer rapidly falls apart as the world and people around him morph and twist into disturbing images. His girlfriend, Jezzie, and ex-wife, Sarah, try to help, but to little avail. Even Singer's chiropractor friend, Louis, fails to reach him as he descends into madness.
Dr. Génessier is riddled with guilt after an accident that he caused disfigures the face of his daughter, the once beautiful Christiane, who outsiders believe is dead. Dr. Génessier, along with accomplice and laboratory assistant Louise, kidnaps young women and brings them to the Génessier mansion. After rendering his victims unconscious, Dr. Génessier removes their faces and attempts to graft them on to Christiane's.
Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.
A research scientist explores the boundaries and frontiers of consciousness. Using sensory deprivation and hallucinogenic mixtures from native American shamans, he explores these altered states of consciousness and finds that memory, time, and perhaps reality itself are states of mind.
Plagued by frightening occurrences in their home, Kelly and Ben learn that a university's parapsychology experiment produced an entity that is now haunting them. The malevolent spirit feeds on fear and torments the couple no matter where they run. Desperate, Kelly and Ben turn to a paranormal researcher, but even with his aid, it may already be too late to save themselves from the terrifying presence.
As a deadly virus ravages the world, Dr. Martin Lowery embarks on a mission to reach test site ATU327A, a research hub deep in the Arboreal Forest. The arduous journey, guided by park scout Alma, is set back by a nighttime attack that leaves the two bruised and shoeless. When they run into Zach, a man living off the grid, they gratefully accept his help. Zach’s intentions aren’t exactly what they seem, however, and a path out of the forest and into safety quickly fades as the line between myth and science blurs.
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