After an overly ambitious businessman transports an 80-foot python to the United States, the beast escapes and starts to leave behind a trail of human victims. An FBI agent and a snake specialist come up with a plot to combat the creature by pitting it against a bioengineered, 70-foot boa constrictor. It's two great snakes that snake great together!
A team of environmentalists, including a reporter, her camera man, and an environmentalist's famous girlfriend charter a boat and with the captain, sail to a military island. They suspect the island is hosting to illegal activities. Upon arrival, however, they find no one. They finally reach a deserted house, where they find Dr. Susan Richardson, who tells them that everyone on the island is dead, including her father. Richardson's team were working on a compound that could make edible plants grow to super size, however the military intervened with plans of their own. They wanted to test the compound's effects on animals, and proceeded to feed it to several komodo dragons and cobras.
Under a powerful Mayan curse, snakes are hatched inside a young woman, slowly devouring her from within. Her only chance for survival is a powerful shaman who lives across the border. With only hours to live, she jumps on a train headed for Los Angeles. Unfortunately for the passengers aboard, they are now trapped, soon to be victims of these flesh-eating vipers.
A group of American tourists heading down an African river make a brief stop at Snake Island, an island that has been virtually abandoned for years. When they end up getting trapped on the island overnight, they find thousands of deadly snakes intent on reclaiming the tropical island for themselves.
In the countryside, the boy Alan and his friend Becky steal a creepy wooden box with a powerful voodoo stick inside from his voodooistic neighbor. When the boy draws with the stick, his drunken father is attacked by a snake and vanishes. Years later, Alan and Becky are married to each other; while planting some flowers to celebrate the death of Alan's mother, Becky finds the box buried in the garden and she keeps the stick in her pocket. Meanwhile, five friends are traveling in a monster truck, drinking beer. The driver accidentally runs over Becky, but believes he had hit an animal. When Alan witnesses the hit-and-run and sees his wife dead, he uses the stick seeking revenge against the youngsters.
In the wake of a young Jewish girl’s disappearance, the son of a Hasidic funeral director returns home with his pregnant wife in hopes of reconciling with his father. Little do they know that directly beneath them in the family morgue, an ancient evil with sinister plans for the unborn child lurks inside a mysterious corpse.
In 1815 a monk, Tomas Alcala, unwittingly unleashes two female succubi, Munkar and Nakir, upon an unsuspecting 21st century. He is chosen by God to travel through the centuries and stop the demons' rampage.
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